Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006586
Fusion event
HBV-GLYATL1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1732
Integrated sequence
ACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTC| |CGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGG
Host Sequence
Chromosome
chr11
Cytoband
q12.1
Reference genome
Start
End
58955636 (Hg38)
Location type
Exon
Target gene
Nearest miRNA
hsa-mir-129-2/Upstream/1314350; hsa-let-7a-2/Downstream/639441;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/49821, chr11-CpG: 19/Downstream/8202
Downstream sequence
AGCTGGATGTCTCTTATTC
Junction sequence
AAGACTGTTTGTTTAAGGACAGCTGGATGTCTCTTATTC
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.