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VISDB
Viral Integration Site DataBase
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TVIS10006589
Basic Information
VIS ID
TVIS10006589
Fusion event
HBV-LOC105374464 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1815
Integrated sequence
CCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAA| |ACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGT
Host Sequence
Chromosome
chr2
Cytoband
p22.2
Reference genome
GRCh38
Start
37547391 (Hg38)
End
37547391 (Hg38)
Location type
Intronic
Target gene
LOC105374464
Nearest miRNA
hsa-mir-1301/Upstream/2075905; hsa-mir-10b/Downstream/9830284;
Nearest TSS
ENST00000437798/Upstream/179110;
ENST00000419425/Downstream/52745;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/202137
,
chr2-CpG: 167/Downstream/123608
Nearby gene
QPCT
(-174564) ;
CDC42EP3
(+94490) ;
Downstream sequence
TCGTGGGGTGACAAAGGGG
Junction sequence
TTGGTCTGCGCACCAGCACCTCGTGGGGTGACAAAGGGG
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
12
Sample type
Tumor
Age
16
Gender
Female
CpG Island Information
×
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