VISDB Viral Integration Site DataBase

VIS ID

TVIS10006595

Fusion event

HBV-MECP2 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1821

Integrated sequence

GAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATG| |TATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGAT

Chromosome

chrX

Cytoband

q28

Reference genome

Start

End

154096037 (Hg38)

Location type

Intron

Fragile sites / regions

FRAXE ; FRAXF

Target gene

miRNAs that regulate target gene

hsa-mir-802 ; hsa-mir-155-5p ; hsa-mir-199a-3p ; hsa-mir-195-5p ; hsa-mir-19a-3p ; hsa-mir-122-5p ; hsa-mir-212-3p ; hsa-mir-199a-5p ; hsa-mir-124-3p ; hsa-mir-148b-3p ; hsa-mir-425-3p ; hsa-mir-331-3p ; hsa-mir-92a-3p ; hsa-mir-340-5p ; hsa-mir-181c-5p ; hsa-mir-3156-3p ; hsa-mir-4301 ; hsa-mir-4279 ; hsa-mir-30a-3p ; hsa-mir-432-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-5591-3p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-1233-3p ; hsa-mir-1253 ; hsa-mir-3162-3p ; hsa-mir-5197-3p ; hsa-mir-6501-3p ; hsa-mir-660-5p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-4428 ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-892b ; hsa-mir-548ao-3p ; hsa-mir-653-5p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-6864-5p ; hsa-mir-6126 ; hsa-mir-4312 ; hsa-mir-1252-5p ; hsa-mir-138-1-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-17-5p ; hsa-mir-106a-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6749-3p ; hsa-mir-4313 ; hsa-mir-942-5p ; hsa-mir-3121-5p ; hsa-mir-1250-3p ; hsa-mir-130a-3p ; hsa-mir-1286 ; hsa-mir-2278 ; hsa-mir-3140-3p ; hsa-mir-4433a-3p ; hsa-mir-4433b-3p ; hsa-mir-4468 ; hsa-mir-4481 ; hsa-mir-4722-5p ; hsa-mir-4745-5p ; hsa-mir-6165 ; hsa-mir-6511b-5p ; hsa-mir-656-5p ; hsa-mir-659-3p ; hsa-mir-6811-5p ; hsa-mir-8083 ; hsa-mir-873-5p

Nearest miRNA

hsa-let-7f-2/Upstream/76048; hsa-mir-1184-1/Downstream/354283;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/75833, chrX-CpG: 108/Downstream/1073

Upstream sequence

ATGTTACTACTGAGGCCGTA

Junction sequence