VISDB Viral Integration Site DataBase

VIS ID

TVIS10006596

Fusion event

HBV-CCDC170 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1816

Integrated sequence

CCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAA| |CGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTA

Chromosome

chr6

Cytoband

q25.1

Reference genome

Start

End

151518831 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-122-5p ; hsa-mir-1267 ; hsa-mir-1307-3p ; hsa-mir-143-5p ; hsa-mir-3135b ; hsa-mir-3652 ; hsa-mir-367-5p ; hsa-mir-4423-5p ; hsa-mir-4430 ; hsa-mir-4638-5p ; hsa-mir-504-3p ; hsa-mir-6501-5p ; hsa-mir-6817-3p ; hsa-mir-744-3p ; hsa-mir-1273f ; hsa-mir-143-3p ; hsa-mir-4251 ; hsa-mir-4303 ; hsa-mir-4329 ; hsa-mir-4703-3p ; hsa-mir-4708-5p ; hsa-mir-4762-3p ; hsa-mir-4770 ; hsa-mir-6088 ; hsa-mir-6761-5p ; hsa-mir-7852-3p

Nearest miRNA

hsa-mir-10398/Upstream/416055; hsa-mir-1202/Downstream/3334529;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/24439, chr6-CpG: 105/Downstream/288856

Upstream sequence

GCAGGTTTTTATTAAGGACT

Junction sequence