VISDB Viral Integration Site DataBase

VIS ID

TVIS10006597

Fusion event

HBV-TPK1 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1829

Integrated sequence

GTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTG| |CGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGAG

Chromosome

chr7

Cytoband

q35

Reference genome

Start

End

144526314 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-3064-3p ; hsa-mir-4704-3p ; hsa-mir-4717-3p ; hsa-mir-371a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p

Nearest miRNA

hsa-mir-10399/Upstream/1143514; hsa-mir-153-2/Downstream/2851703;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/122267, chr7-CpG: 66/Downstream/309355

Downstream sequence

TGAAAAAGATTTTGAGATAG

Junction sequence