VISDB Viral Integration Site DataBase

VIS ID

TVIS10006605

Fusion event

HBV-ARHGEF3 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1804

Integrated sequence

GTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAG| |CAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGG

Chromosome

chr3

Cytoband

p14.3

Reference genome

Start

End

56852545 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-138-5p ; hsa-mir-373-3p ; hsa-mir-335-5p ; hsa-mir-769-5p ; hsa-mir-377-5p ; hsa-mir-485-5p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-889-3p ; hsa-mir-4793-5p ; hsa-mir-5196-3p

Nearest miRNA

hsa-let-7g/Upstream/999951; hsa-mir-12124/Downstream/3765260;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/50363, chr3-CpG: 112/Downstream/226176

Downstream sequence

TGTTTTTTCAAATTCTCTA

Junction sequence