VISDB Viral Integration Site DataBase

VIS ID

TVIS10006606

Fusion event

HBV-PLPP3 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1711

Integrated sequence

CCGGCAGATGAGAAGGCACAGACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAA| |GCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCAT

Chromosome

chr1

Cytoband

p32.2

Reference genome

Start

End

56570009 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-7-5p ; hsa-mir-98-5p ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-4531 ; hsa-mir-6883-3p ; hsa-mir-5192 ; hsa-mir-5186 ; hsa-mir-3120-5p ; hsa-mir-4502 ; hsa-mir-3162-3p ; hsa-mir-181b-5p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p ; hsa-mir-4262 ; hsa-mir-185-5p ; hsa-mir-4306 ; hsa-mir-4644 ; hsa-mir-451b ; hsa-mir-2278 ; hsa-mir-4511 ; hsa-mir-15a-5p ; hsa-mir-424-5p ; hsa-mir-15b-5p ; hsa-mir-16-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-195-5p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-138-2-3p ; hsa-mir-6809-3p ; hsa-mir-6827-3p ; hsa-mir-340-3p ; hsa-mir-4279 ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-6789-3p ; hsa-mir-6778-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-150-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6814-5p ; hsa-mir-5697 ; hsa-mir-1295b-3p ; hsa-mir-625-3p ; hsa-mir-562 ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-6887-3p ; hsa-mir-122-3p ; hsa-mir-184

Nearest miRNA

hsa-mir-12136/Upstream/1344286; hsa-mir-101-1/Downstream/3163218;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/92012, chr1-CpG: 95/Downstream/8420

Downstream sequence

CTTATATAGTGTTTGTCA

Junction sequence