VISDB Viral Integration Site DataBase

VIS ID

TVIS10006610

Fusion event

HBV-BCL3 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

2288

Integrated sequence

TCGTTGACATACTTTCCAATCAATAGGCCTGTTAATAGGAAGTTTTCTAAAACATTCTTTGATTTTTTGTATGATGTGTTCTTGTGGCAAGGACCCATAA| |CATCCAATGACATAACCCATAAAATTTAGAGAGTAACCCCATCTCTTTGTTTTGTTAGGGTTTAAATGTATACCCAAAGACAAAAGAAAATTGGTAACAG

Chromosome

chr19

Cytoband

q13.32

Reference genome

Start

End

44757015 (Hg38)

Location type

at intron-exon junction

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-125b-5p ; hsa-mir-26b-5p ; hsa-mir-1229-5p ; hsa-mir-3115 ; hsa-mir-5197-3p ; hsa-mir-6732-5p ; hsa-mir-6747-5p ; hsa-mir-6752-5p ; hsa-mir-6772-5p ; hsa-mir-6842-5p ; hsa-mir-7110-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-4666b ; hsa-mir-3936 ; hsa-mir-3132 ; hsa-mir-197-5p ; hsa-mir-3934-3p ; hsa-mir-133a-3p ; hsa-mir-7109-5p ; hsa-mir-4281 ; hsa-mir-6885-5p ; hsa-mir-328-5p ; hsa-mir-6887-5p ; hsa-mir-6795-5p ; hsa-mir-486-3p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-4671-5p ; hsa-mir-7161-3p ; hsa-mir-5586-3p ; hsa-mir-4662b ; hsa-mir-4647 ; hsa-mir-4426 ; hsa-mir-759

Nearest miRNA

hsa-mir-10395/Upstream/103283; hsa-let-7e/Downstream/1642;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/2354, chr19-CpG: 114/Downstream/80

Nearest cancer related gene

BCL3(OG, No orient, 0)

Downstream sequence

AGACACCGCTCCACCTGG

Junction sequence