Basic Information
VIS ID
TVIS10006612
Fusion event
HBV-LOC105370767 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr15
Cytoband
q14
Reference genome
GRCh38
Start
36350632 (Hg38)
End
36350632 (Hg38)
Location type
Intronic
Target gene
LOC105370767
Nearest miRNA
hsa-mir-1233-1/Upstream/423709; hsa-mir-10393/Downstream/622189;
Nearest TSS
ENST00000557528/Upstream/8893; ENST00000567573/Downstream/93880;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/804318, chr15-CpG: 35/Downstream/228626
Nearby gene
MIR4510(-423709) ; C15orf41(+228970) ;
Upstream sequence
ttttaacatccttatacctcctgttatttttttcatttatgtttatcattttctcattgTTAACAACAGCAATGCTAGAAAAGAGATATTAACACTTTGC
Downstream sequence
TTATGTTTTTATGTTGCAAATATCTCTTCCTACTTTGTCCTTTTGTCTTTTAATTTTGTTTATGCTTTAAGTTTGTTCATGATTTTATGATTTTTCTCTT
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate