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VISDB
Viral Integration Site DataBase
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TVIS10006617
Basic Information
VIS ID
TVIS10006617
Fusion event
HBV-LOC101929507 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1802
Integrated sequence
GAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCT| |AGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTA
Host Sequence
Chromosome
chr9
Cytoband
p23
Reference genome
GRCh38
Start
13895619 (Hg38)
End
13895619 (Hg38)
Location type
Intronic
Target gene
LOC101929507
Nearest miRNA
hsa-mir-101-2/Upstream/7887715; hsa-let-7a-1/Downstream/4677687;
Nearest TSS
ENST00000422679/Upstream/449128;
ENST00000381010/Downstream/32352;
Nearest CpG islands
None/Target,
chr9-CpG: 64/Upstream/572268
,
chr9-CpG: 242/Downstream/417334
Nearby gene
LINC01235
(-464290) ;
LINC00583
(+32351) ;
Downstream sequence
AGCAAGTCACAAAAATTC
Junction sequence
CTGTAGGCATAAATTGGTCTTANAGCAAGTCACAAAAATTC
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
13
Sample type
Tumor
Age
17
Gender
Female
CpG Island Information
×
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