Basic Information
VIS ID
TVIS10006619
Fusion event
HBV-LOC100507412 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1829
Integrated sequence
GTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTG| |CGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGAG
Host Sequence
Chromosome
chr21
Cytoband
p11.2
Reference genome
GRCh38
Start
8218570 (Hg38)
End
8218570 (Hg38)
Location type
Intron
Target gene
LOC100507412
Nearest miRNA
hsa-mir-10401/Upstream/9918; hsa-let-7c/Downstream/30935;
Nearest TSS
ENST00000624081/Upstream/7264; ENST00000623860/Downstream/36944;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/16167, chr21-CpG: 239/Downstream/459
Upstream sequence
GGATTATGACTGAACGCCTC
Junction sequence
GGATTATGACTGAACGCCTCTGAAAAAGTTGCATGGTGCT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate