Basic Information
VIS ID
TVIS10006620
Fusion event
HBV-LOC105371975 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1746
Integrated sequence
TAAAGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCG| |CCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGA
Host Sequence
Chromosome
chr18
Cytoband
p11.23
Reference genome
GRCh38
Start
7331602 (Hg38)
End
7331602 (Hg38)
Location type
Intronic
Target gene
LOC105371975
Nearest miRNA
hsa-mir-3976/Upstream/957177; hsa-mir-1-2/Downstream/3427982;
Nearest TSS
ENST00000575820/Upstream/100477; ENST00000578916/Downstream/235180;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/213360, chr18-CpG: 285/Downstream/234957
Nearby gene
LRRC30(-99558) ; PTPRM(+236216) ;
Downstream sequence
TTCTGCCTCCCGGGTTCA
Junction sequence
AAGGACTGGGAGGAGTTGGGTTCTGCCTCCCGGGTTCA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate