MLANA _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006621
Fusion event
HBV-MLANA integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr9
Cytoband
p24.1
Reference genome
GRCh38
Start
5896764 (Hg38)
End
5896764 (Hg38)
Location type
Intron
Target gene
MLANA
miRNAs that regulate target gene
hsa-mir-7856-5p ; hsa-mir-499a-5p ; hsa-mir-4645-3p ; hsa-mir-144-3p ; hsa-mir-562 ; hsa-mir-4432 ; hsa-mir-8087
Nearest miRNA
hsa-mir-101-2/Upstream/1046389; hsa-let-7a-1/Downstream/111062;
Nearest TSS
ENST00000422679/Upstream/4253; ENST00000490518/Downstream/800;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/63503, chr9-CpG: 135/Downstream/110200
Nearest cancer related gene
MLANA(OG, No orient, 0)
Junction sequence
CTTTGTGGTAACTGTAAT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate