Basic Information
VIS ID
TVIS10006631
Fusion event
HBV-chr12 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1771
Integrated sequence
GTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGT| |CCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCT
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
GRCh38
Start
98467233 (Hg38)
End
98467233 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7i/Upstream/471785; hsa-mir-1178/Downstream/1722651;
Nearest TSS
ENST00000382841/Upstream/174788; ENST00000548911/Downstream/23853;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/10009, chr12-CpG: 25/Downstream/36593
Nearby gene
SLC9A7P1(-10088) ; LINC02453(+18310) ;
Upstream sequence
TAAAATTTCTCTTGCAG
Junction sequence
TAAAATTTCTCTTGCAGAAAGACCTTTAACCTAATCT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate