VISDB Viral Integration Site DataBase

VIS ID

TVIS10006632

Fusion event

HBV-CYP2C19 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1769

Integrated sequence

CGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGAC| |GTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTG

Chromosome

chr10

Cytoband

q23.33

Reference genome

Start

End

94808237 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6516-5p ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-455-3p ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-6880-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-4683 ; hsa-mir-6499-3p ; hsa-mir-767-5p ; hsa-mir-6134 ; hsa-mir-4537 ; hsa-mir-5186 ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-3180-5p ; hsa-mir-3912-5p ; hsa-mir-874-3p ; hsa-mir-3157-3p ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-6886-3p ; hsa-mir-938 ; hsa-mir-6780b-3p ; hsa-mir-10b-3p ; hsa-mir-29a-3p

Nearest miRNA

hsa-mir-107/Upstream/5215410; hsa-mir-1287/Downstream/1256078;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/262101, chr10-CpG: 63/Downstream/375201

Downstream sequence

GGCCAGTATAATGT

Junction sequence