ARHGAP28 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006637
Fusion event
HBV-ARHGAP28 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr18
Cytoband
p11.31
Reference genome
GRCh38
Start
6873174 (Hg38)
End
6873174 (Hg38)
Location type
Intron
Target gene
ARHGAP28
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-196a-5p ; hsa-mir-98-5p
Nearest miRNA
hsa-mir-3976/Upstream/498749; hsa-mir-1-2/Downstream/3886410;
Nearest TSS
ENST00000575820/Upstream/22383; ENST00000579245/Downstream/292;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/143136, chr18-CpG: 27/Downstream/47418
Upstream sequence
TAAGGGCCATGGTGTGTGCATTCCATGTGGTGCCTGACATGTATGTTGTTTGACAATATTGGGTGTTCCTTATAAAGAAGGCAGTTTCCACAGTTGCAAT
Downstream sequence
GGCAATGTTATCATATACTTTAGACTGCTGTTTTGCTTCTAATTAGCATAGCAGTGATCTGCACATTGTTCTAAACCACATATTCATATTTCTAGGATGC
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
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