Basic Information
VIS ID
TVIS10006638
Fusion event
HBV-chr1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
GRCh38
Start
238589902 (Hg38)
End
238589902 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/1118711; hsa-mir-3123/Downstream/2542370;
Nearest TSS
ENST00000473358/Upstream/103879; ENST00000481779/Downstream/660916;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/805754, chr1-CpG: 91/Downstream/797053
Nearby gene
LOC100130331(-661583) ;
Upstream sequence
atgattttcttttggtgaaTGTTCTTATCACTGATAAATTACTCTAAGAACAATGCCCTAGATTGCAGGCAAATTCATTTGTTAGTGCTTTCCAGAATCT
Downstream sequence
ACCtgcggtggtcatgattcttcttccactaacgtggttccataaaaatatcacagctatccctttaaatcaagttcaatctgaatgtatgaccctatcc
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate