Basic Information
VIS ID
TVIS10006642
Fusion event
HBV-chr4 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr4
Cytoband
q34.3
Reference genome
GRCh38
Start
180692756 (Hg38)
End
180692756 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/6268892; hsa-mir-1305/Downstream/1476537;
Nearest TSS
ENST00000502981/Upstream/1227451; ENST00000512480/Downstream/66282;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/633290, chr4-CpG: 20/Downstream/1448369
Nearby gene
LINC00290(+371333) ;
Upstream sequence
agtggggacatagccaaacagtatcattttacccctgacccctcccaaatctcatgtcctcacatttccaaacacaatcattcctttccaacagcccccc
Downstream sequence
agattgttagctcattccagcattaacccaaaagtctaagtccaaagtttcatctgagacaaggcaagtccattccacctatgagcctgtaaaatcaaaa
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate