Basic Information
VIS ID
TVIS10006646
Fusion event
HBV-LOC101928359 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1813
Integrated sequence
GACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGG| |AAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCA
Host Sequence
Chromosome
chrX
Cytoband
q25
Reference genome
GRCh38
Start
122468185 (Hg38)
End
122468185 (Hg38)
Location type
Intronic
Target gene
LOC101928359
Nearest miRNA
hsa-let-7f-2/Upstream/1097132; hsa-mir-105-1/Downstream/11701193;
Nearest TSS
ENST00000429181/Upstream/596316; ENST00000616590/Downstream/715968;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/1420069, chrX-CpG: 29/Downstream/716715
Nearby gene
GRIA3(+716057) ;
Upstream sequence
TGTTTTTCCGATAGAT
Junction sequence
TGTTTTTCCGATAGATATGATGGTGCGCAGACCAAT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate