Basic Information
VIS ID
TVIS10006649
Fusion event
HBV-LOC101929485 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1810
Integrated sequence
AGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCA| |TGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCC
Host Sequence
Chromosome
chr3
Cytoband
q13.11
Reference genome
GRCh38
Start
106417444 (Hg38)
End
106417444 (Hg38)
Location type
Intronic
Target gene
LOC101929485
Nearest miRNA
hsa-let-7g/Upstream/2893328; hsa-mir-12124/Downstream/3185384;
Nearest TSS
ENST00000440867/Upstream/547892; ENST00000473550/Downstream/712547;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/548070, chr3-CpG: 49/Downstream/823118
Nearby gene
CBLB(-548401) ; LINC00882(+692345) ;
Downstream sequence
TGTAAACAAACATAAAGACGCA
Junction sequence
GGCATAAATTGGTCTGCTCACCATGTAAACAAACATAAAGACGCA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate