VISDB Viral Integration Site DataBase

VIS ID

TVIS10006653

Fusion event

HBV-ZZZ3 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1826

Integrated sequence

GTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATAT| |TTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCA

Chromosome

chr1

Cytoband

p31.1

Reference genome

Start

End

77621722 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-548aw ; hsa-mir-6071 ; hsa-mir-6828-3p ; hsa-mir-7158-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-3182 ; hsa-mir-767-3p ; hsa-mir-5688 ; hsa-mir-495-3p

Nearest miRNA

hsa-mir-101-1/Upstream/561520; hsa-mir-11399/Downstream/7512072;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/339183, chr1-CpG: 94/Downstream/60810

Downstream sequence

CAGGAGGATTTCCTGTGCC

Junction sequence