Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006654
Fusion event
HBV-GTF2IRD1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
Start
End
74481611 (Hg38)
Location type
Intron
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1183/Upstream/290317; hsa-mir-10399/Downstream/114357;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/831, chr7-CpG: 40/Downstream/124864
Upstream sequence
GTAATACTTACCTTAGGTGACTTAGAAAATACAGAAAAGTAGAGGGAAGCAAAGTCAGGCATGGATCCCACCCTGAGATGCACGGTCTGGAGTTTGCATC
Downstream sequence
CCGGGCTGCACTGTGTATGCCCCTGAGGTCATCCTGTCCAGTGTTGGAATCAGCCTCTGCTGGGCATCAGGTTGCCTGCACCTACTCCTTGTTTATATGT
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.