VISDB Viral Integration Site DataBase

VIS ID

TVIS10006659

Fusion event

HBV-L2HGDH integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1829

Integrated sequence

GTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTG| |CGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGAG

Chromosome

chr14

Cytoband

q21.3

Reference genome

Start

End

50308450 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-20a-5p ; hsa-mir-126-5p ; hsa-mir-202-5p ; hsa-mir-337-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-4326 ; hsa-mir-4433a-5p ; hsa-mir-1224-3p ; hsa-mir-4709-5p ; hsa-mir-4255 ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-511-5p ; hsa-mir-623 ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-4711-3p ; hsa-mir-6830-3p ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-6780b-3p ; hsa-mir-4780 ; hsa-mir-2114-5p ; hsa-mir-5588-3p ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-1277-5p ; hsa-mir-4795-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-6083 ; hsa-mir-1229-5p ; hsa-mir-1225-5p ; hsa-mir-6728-5p ; hsa-mir-6842-3p ; hsa-mir-503-3p ; hsa-mir-5187-5p ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-5589-5p ; hsa-mir-3189-3p ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-889-5p ; hsa-mir-4482-5p ; hsa-mir-3130-5p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-4506 ; hsa-mir-4684-5p ; hsa-mir-942-5p ; hsa-mir-1251-5p ; hsa-mir-4762-5p ; hsa-mir-517-5p ; hsa-mir-370-5p ; hsa-mir-6787-3p ; hsa-mir-6827-3p ; hsa-mir-340-3p ; hsa-mir-6736-3p ; hsa-mir-1306-5p ; hsa-mir-216a-5p ; hsa-mir-1247-3p ; hsa-mir-126-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-2467-3p ; hsa-mir-3612 ; hsa-mir-377-5p ; hsa-mir-4257 ; hsa-mir-455-3p ; hsa-mir-487b-3p ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-6807-5p

Nearest miRNA

hsa-mir-208a/Upstream/8504; hsa-mir-1185-1/Downstream/3639977;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/76380, chr14-CpG: 84/Downstream/3512

Downstream sequence

ATACACAGATGGCAAAGAAGCAC

Junction sequence