VISDB Viral Integration Site DataBase

VIS ID

TVIS10006660

Fusion event

HBV-SLAIN2 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1787

Integrated sequence

GAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAG| |TTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAG

Chromosome

chr4

Cytoband

p11

Reference genome

Start

End

48345308 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-20b-5p ; hsa-mir-520e ; hsa-mir-519c-3p ; hsa-mir-520a-3p ; hsa-mir-519b-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-519d-3p ; hsa-mir-520d-3p ; hsa-mir-519a-3p ; hsa-mir-302e ; hsa-mir-153-3p ; hsa-mir-376a-5p ; hsa-mir-135b-3p ; hsa-mir-3679-3p ; hsa-mir-4756-3p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-203a-3p ; hsa-mir-126-5p ; hsa-mir-190a-3p ; hsa-mir-409-3p ; hsa-mir-510-3p ; hsa-mir-944 ; hsa-mir-4760-5p ; hsa-mir-5011-5p ; hsa-mir-8061 ; hsa-mir-218-5p ; hsa-mir-4446-5p ; hsa-mir-3674 ; hsa-mir-4733-3p ; hsa-mir-1226-3p ; hsa-mir-154-5p ; hsa-mir-129-5p ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-4684-3p

Nearest miRNA

hsa-mir-12113/Upstream/692565; hsa-mir-1243/Downstream/4367374;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/2996, chr4-CpG: 95/Downstream/138018

Downstream sequence

CAGAGTAAATAATCCCAGTT

Junction sequence