Basic Information
VIS ID
TVIS10006666
Fusion event
HBV-LOC107984222 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1786
Integrated sequence
GGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCA| |GTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGA
Host Sequence
Chromosome
chr10
Cytoband
p11.21
Reference genome
GRCh38
Start
36055897 (Hg38)
End
36055897 (Hg38)
Location type
Intronic
Target gene
LOC107984222
Nearest miRNA
hsa-mir-1265/Upstream/414645; hsa-mir-107/Downstream/6941666;
Nearest TSS
ENST00000439456/Upstream/156934; ENST00000426283/Downstream/33492;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/290446, chr10-CpG: 51/Downstream/1069320
Nearby gene
PCAT5(-254977) ;
Downstream sequence
GTCCATTCTTCTCATC
Junction sequence
TCTTTGTATTAGGAGGCTGTGTCCATTCTTCTCATC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate