Basic Information
VIS ID
TVIS10006677
Fusion event
HBV-chr15 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1828
Integrated sequence
CGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTT| |GCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGA
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
GRCh38
Start
88988718 (Hg38)
End
88988718 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10393/Upstream/376784; hsa-mir-1302-10/Downstream/338021;
Nearest TSS
ENST00000557528/Upstream/75307; ENST00000565938/Downstream/52505;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/75119, chr15-CpG: 59/Downstream/99597
Nearby gene
MFGE8(-75286) ; ABHD2(+99431) ;
Upstream sequence
AGGGGAATTGCAATAGAGAAA
Junction sequence
AGGGGAATTGCAATAGAGAAAGAAAAAGTTGCATGGTGCTG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate