hsa-mir-422a _LIHC.png
NT5E _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006678
Fusion event
HBV-NT5E integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1910
Integrated sequence
TGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCC| |GCAGTATGGATCGGCAGAGGAGCCGAAAAGGTTCCACGCATGCGCTGATGGCCCATGACCAAGCCCCAGCCAGTGGGGGTTGCGTCAGCAAACACTTGGC
Host Sequence
Chromosome
chr6
Cytoband
q14.3
Reference genome
GRCh38
Start
85461810 (Hg38)
End
85461810 (Hg38)
Location type
Intron
Target gene
NT5E
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-30a-5p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-34a-5p ; hsa-mir-422a
Nearest miRNA
hsa-mir-10398/Upstream/6922501; hsa-mir-1202/Downstream/4850932;
Nearest TSS
ENST00000381078/Upstream/11719; ENST00000437581/Downstream/9571;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/11133, chr6-CpG: 107/Downstream/131585
Upstream sequence
AGGCCTGGCACCCCTCTCTCT
Junction sequence
AGGCCTGGCACCCCTCTCTCTACAATGTCCATGCCCCAAAGC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate