VISDB Viral Integration Site DataBase

VIS ID

TVIS10006682

Fusion event

HBV-RHBDF2 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

531

Integrated sequence

GTGTAAATAGTGTCTAGTTTGGAAGTAATGATTAACTAGATGTTCTGGATAATAAGGTTTAATACCCTTATCCAATGGTAAATATTTGGTAACCTTTGGA| |TAAAACCTGGCAGGCATAATCAATTGCAATCTTCTTTTCTCATTAACTGTGAGTGGGCCTACAAACTGTTCACATTTTTTGATAATGTCTTGGTGTAAAT

Chromosome

chr17

Cytoband

q25.1

Reference genome

Start

End

76492339 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-7-5p ; hsa-mir-98-5p ; hsa-mir-615-3p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-2467-3p ; hsa-mir-3125 ; hsa-mir-3150b-3p ; hsa-mir-3179 ; hsa-mir-3202 ; hsa-mir-3622b-5p ; hsa-mir-3916 ; hsa-mir-4253 ; hsa-mir-4257 ; hsa-mir-4266 ; hsa-mir-4436b-3p ; hsa-mir-4458 ; hsa-mir-4476 ; hsa-mir-4500 ; hsa-mir-4632-5p ; hsa-mir-4688 ; hsa-mir-4695-5p ; hsa-mir-4779 ; hsa-mir-4784 ; hsa-mir-583 ; hsa-mir-6735-5p ; hsa-mir-6743-5p ; hsa-mir-6859-5p ; hsa-mir-6862-5p ; hsa-mir-6876-5p ; hsa-mir-6879-5p ; hsa-mir-765 ; hsa-mir-7843-5p

Nearest miRNA

hsa-mir-10226/Upstream/394263; hsa-mir-1250/Downstream/244111;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/20265, chr17-CpG: 60/Downstream/8571

Upstream sequence

TGGAGACAGCATAACCCAG

Junction sequence