C16orf86 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006685
Fusion event
HBV-C16orf86 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1855
Integrated sequence
CGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGT| |CCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGAGGAGCCGAAAAGGTTCCACGCATGCGC
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
GRCh38
Start
67667074 (Hg38)
End
67667074 (Hg38)
Location type
Intron
Fragile sites / regions
FRA16B
Target gene
C16orf86
Nearest miRNA
hsa-mir-1225/Upstream/464679; hsa-mir-11401/Downstream/566352;
Nearest TSS
ENST00000527434/Upstream/184; ENST00000602987/Downstream/191;
Nearest CpG islands
chr16-CpG: 125/Target, None/Upstream, None/Downstream
Upstream sequence
CGCTCAGACCTCCGAGGT
Junction sequence
CGCTCAGACCTCCGAGGTAATGAACATGAGATGATTAGG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
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