Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006686
Fusion event
HBV-FAM71D integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1763
Integrated sequence
CGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACA| |AAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAA
Host Sequence
Chromosome
chr14
Cytoband
q23.3
Reference genome
Start
End
67211985 (Hg38)
Location type
Intron
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-208a/Upstream/1740799; hsa-mir-1185-1/Downstream/229870;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/702468, chr14-CpG: 95/Downstream/29051
Downstream sequence
GCATTCTTCTGCCAGGAGA
Junction sequence
GGGGGAGGAGGTTAGGTTAAGCATTCTTCTGCCAGGAGA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.