Basic Information
VIS ID
TVIS10006687
Fusion event
HBV-chr11 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr11
Cytoband
q12.1
Reference genome
GRCh38
Start
59932181 (Hg38)
End
59932181 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-129-2/Upstream/337023; hsa-let-7a-2/Downstream/276890;
Nearest TSS
ENST00000527297/Upstream/53372; ENST00000644529/Downstream/6251;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/33797, chr11-CpG: 21/Downstream/583129
Nearby gene
TCN1(-65613) ; OOSP1(+10697) ;
Upstream sequence
tgggactggaaaaggcaccagctccctgttgggtctgtgggactggcagcctggtccccaaacttcaggccctccctggcctgaaggagggaccttactg
Downstream sequence
gaaacccacccccttccacttggaactctgtctgcctcctgctgttcatggtgcctgggcttggcctgactttgctctgagattggagcaggtgccgaca
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate