VISDB Viral Integration Site DataBase

VIS ID

TVIS10006689

Fusion event

HBV-MBTD1 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1815

Integrated sequence

CCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAA| |ACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGT

Chromosome

chr17

Cytoband

q21.33

Reference genome

Start

End

51215233 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-151a-3p ; hsa-mir-128-3p ; hsa-mir-101-3p ; hsa-mir-27a-3p ; hsa-mir-149-5p ; hsa-mir-1277-5p ; hsa-mir-7856-5p ; hsa-mir-6083 ; hsa-mir-3658 ; hsa-mir-190a-3p ; hsa-mir-3688-3p ; hsa-mir-8076 ; hsa-mir-5011-5p ; hsa-mir-590-3p ; hsa-mir-5587-5p ; hsa-mir-676-5p ; hsa-mir-6507-3p

Nearest miRNA

hsa-mir-10226/Upstream/446503; hsa-mir-1250/Downstream/5676037;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/47947, chr17-CpG: 150/Downstream/44508

Upstream sequence

TAATCATGTG GTAAGGTTAG

Junction sequence