Basic Information
VIS ID
TVIS10006690
Fusion event
HBV-chr19 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr19
Cytoband
q13.11
Reference genome
GRCh38
Start
33855613 (Hg38)
End
33855613 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/13456259; hsa-let-7e/Downstream/1267087;
Nearest TSS
ENST00000633603/Upstream/41802; ENST00000610908/Downstream/50739;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/35001, chr19-CpG: 127/Downstream/49953
Nearby gene
KCTD15(-39852) ; LSM14A(+316833) ;
Upstream sequence
aaaaactgctttctgaaaggcactttaaaaATAAAGTcttgaagtcaggatttaagaccggcatgggcaacatggtaagactctgtctctactaaaaatg
Downstream sequence
caaaaaattacccaggcatggtggtgcatgtctgtcatcccagctacttggggggggtgaggtgagagaattgtttgagccttggagggtggaggttgca
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate