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VISDB
Viral Integration Site DataBase
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TVIS10006691
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006691
Fusion event
HBV-CSMD2 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1821
Integrated sequence
GAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATG| |TATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGAT
Host Sequence
Chromosome
chr1
Cytoband
p35.1
Reference genome
GRCh38
Start
33546240 (Hg38)
End
33546240 (Hg38)
Location type
Intron
Target gene
CSMD2
miRNAs that regulate target gene
hsa-mir-3941
;
hsa-mir-125b-2-3p
;
hsa-mir-603
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-8485
;
hsa-mir-495-5p
;
hsa-mir-4650-5p
;
hsa-mir-1972
Nearest miRNA
hsa-mir-12136/Upstream/213748; hsa-mir-101-1/Downstream/1123359;
Nearest TSS
ENST00000473358/Upstream/73580;
ENST00000458277/Downstream/26350;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/73513
,
chr1-CpG: 20/Downstream/78765
Downstream sequence
AATCCCATTATTTTTCAGGGA
Junction sequence
GTTCACCAGCACCACACAAAATCCCATTATTTTTCAGGGA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
16
Sample type
Tumor
Age
25
Gender
Female
CpG Island Information
×
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