VISDB Viral Integration Site DataBase

VIS ID

TVIS10006692

Fusion event

HBV-TRIM35 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1803

Integrated sequence

AGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTA| |GCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAG

Chromosome

chr8

Cytoband

p21.2

Reference genome

Start

End

27291710 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-384 ; hsa-mir-7975 ; hsa-mir-568 ; hsa-mir-5571-3p ; hsa-mir-3924 ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-633 ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-4310 ; hsa-mir-7157-5p ; hsa-mir-5692b ; hsa-mir-5692c ; hsa-mir-369-3p ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-4713-5p ; hsa-mir-6881-3p ; hsa-mir-642a-5p ; hsa-mir-188-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-5008-5p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-877-3p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-6870-3p ; hsa-mir-6891-3p ; hsa-mir-6072 ; hsa-mir-5196-3p ; hsa-mir-5000-3p ; hsa-mir-4436a ; hsa-mir-4700-3p ; hsa-mir-1236-3p ; hsa-mir-18a-5p ; hsa-mir-18b-5p ; hsa-mir-4521 ; hsa-mir-4735-3p ; hsa-mir-548ae-3p ; hsa-mir-548ah-3p ; hsa-mir-548aj-3p ; hsa-mir-548am-3p ; hsa-mir-548aq-3p ; hsa-mir-548j-3p ; hsa-mir-548x-3p

Nearest miRNA

hsa-mir-124-1/Upstream/242747; hsa-mir-10400/Downstream/141660;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/3626, chr8-CpG: 89/Downstream/18978

Nearest cancer related gene

TRIM35(TSG, No orient, 0)

Downstream sequence

ATAAACAATAGTTTATT

Junction sequence