Basic Information
VIS ID
TVIS10006697
Fusion event
HBV-LOC112268302 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1801
Integrated sequence
AGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCC| |TAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCT
Host Sequence
Chromosome
chrX
Cytoband
q24
Reference genome
GRCh38
Start
121427083 (Hg38)
End
121427083 (Hg38)
Location type
Intronic
Target gene
LOC112268302
Nearest miRNA
hsa-let-7f-2/Upstream/56030; hsa-mir-105-1/Downstream/12742295;
Nearest TSS
ENST00000429181/Upstream/379495; ENST00000569460/Downstream/444786;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/378967, chrX-CpG: 29/Downstream/1757817
Nearby gene
MIR3672(-56030) ;
Upstream sequence
GTATTATTTAGAACCATTAT
Junction sequence
GTATTATTTAGAACCATTATGACCAATTTANGCNNNCAGC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate