Basic Information
VIS ID
TVIS10006700
Fusion event
HBV-chr2 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr2
Cytoband
p14
Reference genome
GRCh38
Start
65831213 (Hg38)
End
65831213 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1301/Upstream/1305648; hsa-mir-10b/Downstream/527036;
Nearest TSS
ENST00000437798/Upstream/191036; ENST00000412313/Downstream/405000;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/394468, chr2-CpG: 102/Downstream/594523
Nearby gene
SPRED2(-398691) ; MIR4778(+527035) ;
Upstream sequence
aacctcgcctatttcctgatacgctttaagcacaaataaatggtggccattattAGCACTACCACAGGAAAAAGAGACTAGTGCAGTGTGTTGTGGACAT
Downstream sequence
TCACGAAATGCTACTCTctctttatcctgtttatttcctttgtaggcgttatcacagactatatttatttgtgtatgtgtgtttatttatttttcaggtc
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate