Basic Information
VIS ID
TVIS10006701
Fusion event
HBV-chr17 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1897
Integrated sequence
AGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGC| |GGCTAGGAGTTCCGCAGTATGGATCGGCAGAGGAGCCGAAAAGGTTCCACGCATGCGCTGATGGCCCATGACCAAGCCCCAGCCAGTGGGGGTTGCGTCA
Host Sequence
Chromosome
chr17
Cytoband
q22
Reference genome
GRCh38
Start
53822748 (Hg38)
End
53822748 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10226/Upstream/3054018; hsa-mir-1250/Downstream/3068522;
Nearest TSS
ENST00000595228/Upstream/837228; ENST00000268919/Downstream/153;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/65209, chr17-CpG: 42/Downstream/1077757
Nearby gene
C17orf112(-835096) ; KIF2B(+129) ;
Upstream sequence
TTTCTCGCCATGATCCGGA
Junction sequence
TTTCTCGCCATGATCCGGATGCGCAGACCAATTTATGCC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate