Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006702
Fusion event
HBV-SLC26A6 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1792
Integrated sequence
GGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGC| |AGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAA
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
Start
End
48634649 (Hg38)
Location type
Intron
Target gene
Nearest miRNA
hsa-mir-12127/Upstream/951; hsa-let-7g/Downstream/9545;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/24678, chr3-CpG: 77/Downstream/324
Downstream sequence
AGCTTTCACCAGTCAGGAA
Junction sequence
TATTAGGAGGCTGTAGGCATCCAGCTTTCACCAGTCAGGAA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.