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VISDB
Viral Integration Site DataBase
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TVIS10006703
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006703
Fusion event
HBV-CCDC122 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
2344
Integrated sequence
CTTTGATTTTTTGTATGATGTGTTCTTGTGGCAAGGACCCATAACATCCAATGACATAACCCATAAAATTTAGAGAGTAACCCCATCTCTTTGTTTTGTT| |AGGGTTTAAATGTATACCCAAAGACAAAAGAAAATTGGTAACAGCGGTAAAAAGGGACTCAAGATGCTGTACAGACTTGGCCCCCAATACCACATCATCC
Host Sequence
Chromosome
chr13
Cytoband
q14.11
Reference genome
GRCh38
Start
43863539 (Hg38)
End
43863539 (Hg38)
Location type
Intron
Target gene
CCDC122
miRNAs that regulate target gene
hsa-mir-7977
;
hsa-mir-3178
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-6499-5p
;
hsa-mir-383-3p
Nearest miRNA
hsa-mir-2276/Upstream/2295144; hsa-mir-1267/Downstream/332590;
Nearest TSS
ENST00000623511/Upstream/4738;
ENST00000425906/Downstream/11387;
Nearest CpG islands
None/Target,
chr13-CpG: 551/Upstream/75979
,
chr13-CpG: 105/Downstream/15532
Downstream sequence
AAGAAAGTATAAACTGTTT
Junction sequence
AACACTTCCGGAGACTACTGAAGAAAGTATAAACTGTTT
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
17
Sample type
Tumor
Age
25
Gender
Female
CpG Island Information
×
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