Basic Information
VIS ID
TVIS10006707
Fusion event
HBV-chr1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr1
Cytoband
p36.12
Reference genome
GRCh38
Start
22316535 (Hg38)
End
22316535 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/50235; hsa-mir-101-1/Downstream/316723;
Nearest TSS
ENST00000473358/Upstream/172566; ENST00000400239/Downstream/135316;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/30610, chr1-CpG: 18/Downstream/25610
Nearby gene
MIR4418(-50235) ; ZBTB40(+135315) ;
Upstream sequence
CCCTTTAGGTCCTCACA
Junction sequence
CCCTTTAGGTCCTCACATGCAGACCAATTTATGCCTAC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate