Basic Information
VIS ID
TVIS10006708
Fusion event
HBV-chr1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1807
Integrated sequence
CCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAG| |CCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGT
Host Sequence
Chromosome
chr1
Cytoband
p36.21
Reference genome
End
15673431 (Hg38)
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-12136/Upstream/3094408; hsa-mir-101-1/Downstream/1185518;
Nearby gene
RSC1A1(-11709) ; PLEKHM2(+10900) ;
Upstream sequence
TGTTGGCTGTTGTTTCTGC
Junction sequence
TGTTGGCTGTTGTTTCTGCTGCGCAGACCAATTTAT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate