VISDB Viral Integration Site DataBase

VIS ID

TVIS10006711

Fusion event

HBV-PLXNA4 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1779

Integrated sequence

GGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCA| |GGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCT

Chromosome

chr7

Cytoband

q32.3

Reference genome

Start

End

132456666 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-6787-3p ; hsa-mir-4267 ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-1226-3p ; hsa-mir-498 ; hsa-mir-4709-3p ; hsa-mir-6744-5p ; hsa-mir-561-5p ; hsa-mir-5002-3p ; hsa-mir-93-3p ; hsa-mir-6830-5p ; hsa-mir-6873-3p ; hsa-mir-7110-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-1178-3p ; hsa-mir-4666a-5p ; hsa-mir-3166 ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-4666b ; hsa-mir-5011-3p ; hsa-mir-486-3p ; hsa-mir-6817-3p ; hsa-mir-342-3p ; hsa-mir-6852-5p

Nearest miRNA

hsa-mir-10525/Upstream/1579127; hsa-mir-10399/Downstream/578194;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/510929, chr7-CpG: 168/Downstream/119049

Downstream sequence

CCCAGGATGGGCCAGG

Junction sequence