Basic Information
VIS ID
TVIS10006712
Fusion event
HBV-LOC100507053 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr4
Cytoband
q23
Reference genome
GRCh38
Start
99208221 (Hg38)
End
99208221 (Hg38)
Location type
Intron
Target gene
LOC100507053
Nearest miRNA
hsa-mir-12113/Upstream/210761; hsa-mir-1243/Downstream/2032574;
Nearest TSS
ENST00000502981/Upstream/46411; ENST00000509295/Downstream/593;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/119243, chr4-CpG: 40/Downstream/355349
Downstream sequence
AGATTTTTAAGTAACTTCC
Junction sequence
TGTAGGCATAAATTGGTTGTAAGATTTTTAAGTAACTTCC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate