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VISDB
Viral Integration Site DataBase
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TVIS10006713
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006713
Fusion event
HBV-G2E3 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1735
Integrated sequence
GGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGC| |AGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGAT
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh38
Start
30602375 (Hg38)
End
30602375 (Hg38)
Location type
Intron
Target gene
G2E3
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-186-5p
;
hsa-mir-125a-5p
;
hsa-let-7a-5p
;
hsa-mir-9-3p
;
hsa-mir-548v
;
hsa-mir-548au-3p
;
hsa-mir-6509-5p
;
hsa-mir-511-5p
;
hsa-mir-5701
;
hsa-mir-331-5p
;
hsa-mir-585-5p
;
hsa-mir-5682
;
hsa-mir-6830-3p
;
hsa-mir-582-5p
;
hsa-mir-5681b
;
hsa-mir-935
;
hsa-mir-4678
;
hsa-mir-5003-3p
;
hsa-mir-6739-3p
;
hsa-mir-375
;
hsa-mir-921
;
hsa-mir-3606-5p
;
hsa-mir-8068
;
hsa-mir-3682-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-3973
;
hsa-mir-1272
;
hsa-mir-708-3p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-33b-5p
;
hsa-mir-33a-5p
;
hsa-mir-92b-3p
;
hsa-mir-92a-3p
;
hsa-mir-367-3p
;
hsa-mir-363-3p
;
hsa-mir-32-5p
;
hsa-mir-25-3p
;
hsa-mir-548x-3p
;
hsa-mir-548j-3p
;
hsa-mir-548aq-3p
;
hsa-mir-548am-3p
;
hsa-mir-548aj-3p
;
hsa-mir-548ah-3p
;
hsa-mir-548ae-3p
;
hsa-mir-548z
;
hsa-mir-548h-3p
;
hsa-mir-548d-3p
;
hsa-mir-548bb-3p
;
hsa-mir-548ac
Nearest miRNA
hsa-mir-208a/Upstream/2969097; hsa-mir-1185-1/Downstream/412271;
Nearest TSS
ENST00000550708/Upstream/3817;
ENST00000547638/Downstream/372;
Nearest CpG islands
None/Target,
chr14-CpG: 35/Upstream/42769
,
chr14-CpG: 122/Downstream/271774
Upstream sequence
GAAAAGTGTATCTATCCTA
Junction sequence
GAAAAGTGTATCTATCCTAATTATTTTTTTGNGTACTCCAGTCTTTAAATACACAGT
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
18
Sample type
Tumor
Age
28
Gender
Female
CpG Island Information
×
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