Basic Information
VIS ID
TVIS10006720
Fusion event
HBV-LOC105376714 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr15
Cytoband
q21.1
Reference genome
GRCh38
Start
45445807 (Hg38)
End
45445807 (Hg38)
Location type
Intronic
Target gene
LOC105376714
Nearest miRNA
hsa-mir-10393/Upstream/12678; hsa-mir-11181/Downstream/3723263;
Nearest TSS
ENST00000557528/Upstream/3999; ENST00000559960/Downstream/2620;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/15066, chr15-CpG: 123/Downstream/76330
Nearby gene
C15orf48(-12358) ; SLC30A4(+36673) ;
Upstream sequence
GGCTGCGAGGTCAGGAGATGGGGGTTTTCCTCTTGCTCTGCAGGACCTTGGGGAAATCACTCACCAGCTAACGTGTGTCAGTGCTCACCGTGCGCCAGCC
Downstream sequence
ACCTTTGAATCCTCCACAGCCCTTGAGGCTTTTTCAGTGAATGCCGAGAGGCAGGTGCTTTGCCTGGCTGCCATGGCCCTGTAATCAGCAGAGCTGGGAT
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate