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VISDB
Viral Integration Site DataBase
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TVIS10006722
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006722
Fusion event
HBV-CAMTA1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1676
Integrated sequence
TGCGACGTGCAGAGGTGAAGCGAAGTGCACACGGTCCGGCAGATGAGAAGGCACAGACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGTCGG| |AACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGC
Host Sequence
Chromosome
chr1
Cytoband
p36.31
Reference genome
GRCh38
Start
6882297 (Hg38)
End
6882297 (Hg38)
Location type
Intron
Fragile sites / regions
FRA1A
Target gene
CAMTA1
miRNAs that regulate target gene
hsa-mir-129-5p
;
hsa-mir-155-5p
;
hsa-mir-218-5p
;
hsa-mir-34a-5p
;
hsa-mir-96-5p
;
hsa-mir-124-3p
;
hsa-mir-17-5p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
Nearest miRNA
hsa-mir-12136/Upstream/452401; hsa-mir-101-1/Downstream/1984205;
Nearest TSS
ENST00000473358/Upstream/8241;
ENST00000476864/Downstream/131982;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/95991
,
chr1-CpG: 23/Downstream/79644
Nearest cancer related gene
CAMTA1
(TSG, No orient, 0)
Upstream sequence
AACAGGGAGCATATGGCCTGT
Junction sequence
AACAGGGAGCATATGGCCTGTAGAGGCCAAGAGTCCTCTTA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
19
Sample type
Tumor
Age
29
Gender
Female
CpG Island Information
×
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