VISDB Viral Integration Site DataBase

VIS ID

TVIS10006726

Fusion event

HBV-PPM1L integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1817

Integrated sequence

CCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAAC| |GATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTAT

Chromosome

chr3

Cytoband

q25.33

Reference genome

Start

End

160892148 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-4728-5p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6721-5p ; hsa-mir-6731-5p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-4722-5p ; hsa-mir-3616-3p ; hsa-mir-6823-5p ; hsa-mir-4459 ; hsa-mir-3619-5p ; hsa-mir-761 ; hsa-mir-214-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-4779 ; hsa-mir-6165 ; hsa-mir-665 ; hsa-mir-3650 ; hsa-mir-7160-5p ; hsa-mir-3934-3p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4790-3p ; hsa-mir-767-3p ; hsa-mir-4649-3p ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6893-5p ; hsa-mir-940 ; hsa-mir-6808-5p ; hsa-mir-4695-5p ; hsa-mir-490-3p ; hsa-mir-6809-5p ; hsa-mir-31-5p ; hsa-mir-550b-3p ; hsa-mir-4501 ; hsa-mir-34c-3p ; hsa-mir-216a-5p ; hsa-mir-182-5p ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-138-2-3p ; hsa-mir-186-3p ; hsa-mir-103b ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-8056 ; hsa-mir-7977 ; hsa-mir-3165 ; hsa-mir-6880-5p ; hsa-mir-8071 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-138-5p ; hsa-mir-4456 ; hsa-mir-342-3p ; hsa-mir-383-3p ; hsa-mir-1228-3p

Nearest miRNA

hsa-let-7g/Upstream/487323; hsa-mir-1224/Downstream/3279323;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/135449, chr3-CpG: 85/Downstream/212558

Nearest cancer related gene

PPM1L(TSG, No orient, 0)

Upstream sequence

CGGAACTTAAAATAAAATAA A

Junction sequence