VISDB Viral Integration Site DataBase

VIS ID

TVIS10006731

Fusion event

HBV-LTBP2 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1828

Integrated sequence

CGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTT| |GCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGA

Chromosome

chr14

Cytoband

q24.3

Reference genome

Start

End

74508971 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-4520-3p ; hsa-mir-3138 ; hsa-mir-3165 ; hsa-mir-6880-5p ; hsa-mir-8071 ; hsa-mir-4708-3p ; hsa-mir-6730-5p ; hsa-mir-3922-5p ; hsa-mir-4753-5p ; hsa-mir-4435 ; hsa-mir-4423-3p ; hsa-mir-6806-5p ; hsa-mir-4487 ; hsa-mir-3190-5p ; hsa-mir-7113-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-3622a-5p ; hsa-mir-5582-5p ; hsa-mir-4713-5p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-486-5p ; hsa-mir-3184-3p ; hsa-mir-4755-3p ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-6075 ; hsa-mir-6850-3p ; hsa-mir-3940-3p

Nearest miRNA

hsa-mir-208a/Upstream/28767; hsa-mir-1185-1/Downstream/2757247;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/14767, chr14-CpG: 23/Downstream/76893

Downstream sequence

GAGGAAGACAGCCGATGGC

Junction sequence