VISDB Viral Integration Site DataBase

VIS ID

TVIS10006732

Fusion event

HBV-GPR27 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1672

Integrated sequence

TCCATGCGACGTGCAGAGGTGAAGCGAAGTGCACACGGTCCGGCAGATGAGAAGGCACAGACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGG| |TCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTC

Chromosome

chr3

Cytoband

p13

Reference genome

Start

End

71755312 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-374b-3p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-922 ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-1537-3p ; hsa-mir-147b ; hsa-mir-4444 ; hsa-mir-5701 ; hsa-mir-4266 ; hsa-mir-1258 ; hsa-mir-7154-3p ; hsa-mir-658 ; hsa-mir-873-5p ; hsa-mir-4779 ; hsa-mir-4695-5p

Nearest miRNA

hsa-let-7g/Upstream/213223; hsa-mir-12124/Downstream/3459164;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/254, chr3-CpG: 74/Downstream/29605

Nearby gene

GPR27(-135) ; PROK2(+16342) ;

Downstream sequence

GATTGTACTGACTCCTTTGGG

Junction sequence